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Salvianolic Acid B Inhibits Hydrogen Peroxide-Induced Endothelial Cell Apoptosis through Regulating PI3K/Akt Signaling

Overview of attention for article published in PLOS ONE, December 2007
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Title
Salvianolic Acid B Inhibits Hydrogen Peroxide-Induced Endothelial Cell Apoptosis through Regulating PI3K/Akt Signaling
Published in
PLOS ONE, December 2007
DOI 10.1371/journal.pone.0001321
Pubmed ID
Authors

Chen-Li Liu, Li-Xia Xie, Min Li, Siva Sundara Kumar Durairajan, Shinya Goto, Jian-Dong Huang

Abstract

Salvianolic acid B (Sal B) is one of the most bioactive components of Salvia miltiorrhiza, a traditional Chinese herbal medicine that has been commonly used for prevention and treatment of cerebrovascular disorders. However, the mechanism responsible for such protective effects remains largely unknown. It has been considered that cerebral endothelium apoptosis caused by reactive oxygen species including hydrogen peroxide (H(2)O(2)) is implicated in the pathogenesis of cerebrovascular disorders.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 3%
Japan 1 3%
Unknown 29 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 23%
Researcher 3 10%
Student > Postgraduate 3 10%
Professor 2 6%
Student > Bachelor 2 6%
Other 10 32%
Unknown 4 13%
Readers by discipline Count As %
Medicine and Dentistry 8 26%
Agricultural and Biological Sciences 7 23%
Biochemistry, Genetics and Molecular Biology 6 19%
Pharmacology, Toxicology and Pharmaceutical Science 3 10%
Psychology 1 3%
Other 1 3%
Unknown 5 16%