| Title |
Recognition of HIV-1 Peptides by Host CTL Is Related to HIV-1 Similarity to Human Proteins
|
|---|---|
| Published in |
PLOS ONE, September 2007
|
| DOI | 10.1371/journal.pone.0000823 |
| Pubmed ID | |
| Authors |
Morgane Rolland, David C. Nickle, Wenjie Deng, Nicole Frahm, Christian Brander, Gerald H. Learn, David Heckerman, Nebosja Jojic, Vladimir Jojic, Bruce D. Walker, James I. Mullins |
| Abstract |
While human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes preferentially target specific regions of the viral proteome, HIV-1 features that contribute to immune recognition are not well understood. One hypothesis is that similarities between HIV and human proteins influence the host immune response, i.e., resemblance between viral and host peptides could preclude reactivity against certain HIV epitopes. |
Mendeley readers
The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 4% |
| United Kingdom | 1 | 2% |
| Unknown | 46 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 27% |
| Student > Ph. D. Student | 11 | 22% |
| Professor > Associate Professor | 4 | 8% |
| Student > Doctoral Student | 4 | 8% |
| Professor | 2 | 4% |
| Other | 9 | 18% |
| Unknown | 6 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 43% |
| Biochemistry, Genetics and Molecular Biology | 6 | 12% |
| Medicine and Dentistry | 5 | 10% |
| Immunology and Microbiology | 3 | 6% |
| Engineering | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 8 | 16% |