| Title |
Human Muscle Satellite Cells as Targets of Chikungunya Virus Infection
|
|---|---|
| Published in |
PLOS ONE, June 2007
|
| DOI | 10.1371/journal.pone.0000527 |
| Pubmed ID | |
| Authors |
Simona Ozden, Michel Huerre, Jean-Pierre Riviere, Lark L. Coffey, Philippe V. Afonso, Vincent Mouly, Jean de Monredon, Jean-Christophe Roger, Mohamed El Amrani, Jean-Luc Yvin, Marie-Christine Jaffar, Marie-Pascale Frenkiel, Marion Sourisseau, Olivier Schwartz, Gillian Butler-Browne, Philippe Desprès, Antoine Gessain, Pierre-Emmanuel Ceccaldi |
| Abstract |
Chikungunya (CHIK) virus is a mosquito-transmitted alphavirus that causes in humans an acute infection characterised by fever, polyarthralgia, head-ache, and myalgia. Since 2005, the emergence of CHIK virus was associated with an unprecedented magnitude outbreak of CHIK disease in the Indian Ocean. Clinically, this outbreak was characterized by invalidating poly-arthralgia, with myalgia being reported in 97.7% of cases. Since the cellular targets of CHIK virus in humans are unknown, we studied the pathogenic events and targets of CHIK infection in skeletal muscle. |
Mendeley readers
The data shown below were compiled from readership statistics for 232 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Philippines | 1 | <1% |
| French Polynesia | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 228 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 39 | 17% |
| Student > Bachelor | 32 | 14% |
| Researcher | 27 | 12% |
| Student > Master | 26 | 11% |
| Other | 15 | 6% |
| Other | 42 | 18% |
| Unknown | 51 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 59 | 25% |
| Biochemistry, Genetics and Molecular Biology | 33 | 14% |
| Immunology and Microbiology | 31 | 13% |
| Medicine and Dentistry | 24 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
| Other | 22 | 9% |
| Unknown | 57 | 25% |