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LRP1 Functions as an Atheroprotective Integrator of TGFβ and PDGF Signals in the Vascular Wall: Implications for Marfan Syndrome

Overview of attention for article published in PLOS ONE, May 2007
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Title
LRP1 Functions as an Atheroprotective Integrator of TGFβ and PDGF Signals in the Vascular Wall: Implications for Marfan Syndrome
Published in
PLOS ONE, May 2007
DOI 10.1371/journal.pone.0000448
Pubmed ID
Authors

Philippe Boucher, Wei-Ping Li, Rachel L. Matz, Yoshiharu Takayama, Johan Auwerx, Richard G.W. Anderson, Joachim Herz

Abstract

The multifunctional receptor LRP1 controls expression, activity and trafficking of the PDGF receptor-beta in vascular smooth muscle cells (VSMC). LRP1 is also a receptor for TGFbeta1 and is required for TGFbeta mediated inhibition of cell proliferation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 76 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 27%
Researcher 19 25%
Student > Bachelor 11 14%
Student > Postgraduate 4 5%
Professor > Associate Professor 4 5%
Other 10 13%
Unknown 8 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 44%
Medicine and Dentistry 13 17%
Biochemistry, Genetics and Molecular Biology 11 14%
Engineering 3 4%
Immunology and Microbiology 2 3%
Other 3 4%
Unknown 11 14%