Title |
Bringing Molecules Back into Molecular Evolution
|
---|---|
Published in |
PLoS Computational Biology, June 2012
|
DOI | 10.1371/journal.pcbi.1002572 |
Pubmed ID | |
Authors |
Claus O. Wilke |
Abstract |
Much molecular-evolution research is concerned with sequence analysis. Yet these sequences represent real, three-dimensional molecules with complex structure and function. Here I highlight a growing trend in the field to incorporate molecular structure and function into computational molecular-evolution work. I consider three focus areas: reconstruction and analysis of past evolutionary events, such as phylogenetic inference or methods to infer selection pressures; development of toy models and simulations to identify fundamental principles of molecular evolution; and atom-level, highly realistic computational modeling of molecular structure and function aimed at making predictions about possible future evolutionary events. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
France | 2 | 1% |
Brazil | 2 | 1% |
United Kingdom | 2 | 1% |
Finland | 1 | <1% |
Switzerland | 1 | <1% |
Netherlands | 1 | <1% |
New Zealand | 1 | <1% |
Canada | 1 | <1% |
Other | 2 | 1% |
Unknown | 133 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 48 | 32% |
Researcher | 33 | 22% |
Professor > Associate Professor | 11 | 7% |
Student > Bachelor | 11 | 7% |
Student > Master | 11 | 7% |
Other | 28 | 19% |
Unknown | 7 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 84 | 56% |
Biochemistry, Genetics and Molecular Biology | 27 | 18% |
Computer Science | 6 | 4% |
Chemistry | 6 | 4% |
Physics and Astronomy | 3 | 2% |
Other | 11 | 7% |
Unknown | 12 | 8% |