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The Efficiency of the Human CD8+ T Cell Response: How Should We Quantify It, What Determines It, and Does It Matter?

Overview of attention for article published in PLoS Computational Biology, February 2012
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Title
The Efficiency of the Human CD8+ T Cell Response: How Should We Quantify It, What Determines It, and Does It Matter?
Published in
PLoS Computational Biology, February 2012
DOI 10.1371/journal.pcbi.1002381
Pubmed ID
Authors

Marjet Elemans, Nafisa-Katrin Seich al Basatena, Becca Asquith

Abstract

Multidisciplinary techniques, in particular the combination of theoretical and experimental immunology, can address questions about human immunity that cannot be answered by other means. From the turnover of virus-infected cells in vivo, to rates of thymic production and HLA class I epitope prediction, theoretical techniques provide a unique insight to supplement experimental approaches. Here we present our opinion, with examples, of some of the ways in which mathematics has contributed in our field of interest: the efficiency of the human CD8+ T cell response to persistent viruses.

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Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 4%
Germany 1 1%
Sweden 1 1%
Netherlands 1 1%
India 1 1%
United States 1 1%
Unknown 64 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 29%
Student > Ph. D. Student 17 24%
Student > Bachelor 7 10%
Student > Master 5 7%
Student > Doctoral Student 3 4%
Other 10 14%
Unknown 9 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 29%
Medicine and Dentistry 11 15%
Immunology and Microbiology 10 14%
Biochemistry, Genetics and Molecular Biology 9 13%
Computer Science 3 4%
Other 7 10%
Unknown 11 15%