@robbwolf Did you ever see this one? https://t.co/KSvHdVTV0F

@GerardoRiordan8 That's true, but it's a different question from whether a higher dose has the potential to make people more sick than a lower dose. I'm not sure what research has been done on covid, but there is a plausible theory that flu works like t

@lilla_poffen @GunnarBj @davidraxen @BrundinPatrik Kan kanske jämföras med 1918 i viss mån (vi vet inte om influesaviruset blev "farligare" i andra vågen: kanske räcker det som förklaring att första vågen var sent på våren/sommaren). https://t.co/NHHSdnYdU

@ovanavoordning @veteprotein @GunnarBj @kjellhaglund 1918 brukar väl anföras som exempel, men det var speciella omständigheter, och det finns andra förklaringar även där. https://t.co/NHHSdnYdUd

@shalabissas @JohnLilic @ggreenwald @gugachacra Original paper for the statement above: https://t.co/QJzpLX1xDa

@varshit_hathi @nirajvasavada really we need google search for that?? https://t.co/gJVSb6aU3D it has been known since last 100 years.

@apsmunro @BristOliver This is also interesting. https://t.co/1mRueQQzee

RT @invadingpirate: Infectious dose and mortality in successive waves of pandemic flu https://t.co/XNmny9ESIX

Infectious dose and mortality in successive waves of pandemic flu https://t.co/XNmny9ESIX

RT @MedicalReads: 2. Farklı influenza suşları ile gönüllülerde yapılan çalışmalarda semptomların şiddetinde ilk maruz kalınan virüs sayısın…

RT @MedicalReads: 2. Farklı influenza suşları ile gönüllülerde yapılan çalışmalarda semptomların şiddetinde ilk maruz kalınan virüs sayısın…

2. Farklı influenza suşları ile gönüllülerde yapılan çalışmalarda semptomların şiddetinde ilk maruz kalınan virüs sayısına bağlı artış görüldü. Yine 1918 salgınında özellikle genç askerlerin yaşadığı eğitim kamplarında ölüm oranı daha yüksekdi. https://t.c

@honfrsocmed @dinkompismia Det har nästan blivit som vidskepelse på en del håll kring "andra vågen" till följd av detta. Vi vet inte varför andra vågen 1918 slog så hårt (det finns inga isolerade virus från första vågen), men första vågen 1918 kom mitt i s

@PaSwede @Sven_Roman Möjligt, men en faktor som kan vara relevant är att våg 1 1918 toppade mitt i sommaren. https://t.co/nX6xcVMhQ8

@SafaMote @Rwill235 1918 Influenza isn't COVID-19 but this study paints a similar picture. https://t.co/474M7W4cUt

@johnmilbank3 This, a 2010 paper, but I’ve seen discussion around it’s hypothesis that it may not be a/the virus weakening, but rather, public health measures have reduced what my late tropical medicine uncle used to refer to as the “challenge dose” of ini

@AntibioticDoc https://t.co/g1czbOAYu1

@sociopaten @JoacimRocklov Visst kan det öka i höst och vinter, men vid jämförelser med 1918 får vi komma ihåg att den första vågen toppade mitt i sommaren (när omständigheterna är som minst gynnsamma för spridning av influensa). https://t.co/JX5G9bjSUU

@WesPegden @BallouxFrancois It has been proposed that the severity of the second wave of the 1918 pandemic was due to higher infectious dose because conditions were more favorable to transmission during fall than during summer. Might this be similar? https

RT @arpitrage: cc @ashdgandhi, there is some speculation that the second wave in the Influenza epidemic reflects higher household crowding…

cc @ashdgandhi, there is some speculation that the second wave in the Influenza epidemic reflects higher household crowding and greater viral load, slide here by another Gandhi (Monica) https://t.co/FCUe6QssvF https://t.co/7Pktjn0aEF

Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic #cdnpoli #uspoli #cdnpoli #covid_19 https://t.co/VU4smmQKLG

RT @MartinFierro769: 54/n On a essayé d'établir une corrélation sur la base d'hypothèses concernant la grippe espagnole.https://t.co/mpnAXv…

RT @XavierAbadMdG: @RossellRos de la segona onada de la grip espanyola pel tema de la dosi... veure https://t.co/afm729S5y1. I dosi i virul…

@RossellRos de la segona onada de la grip espanyola pel tema de la dosi... veure https://t.co/afm729S5y1. I dosi i virulencia de la infecció també es correlaciona per diverses soques de Salmonella i salmonelosis. i jo crec que també es correlaciona aquí, e

RT @MartinFierro769: 54/n On a essayé d'établir une corrélation sur la base d'hypothèses concernant la grippe espagnole.https://t.co/mpnAXv…

RT @MartinFierro769: 54/n On a essayé d'établir une corrélation sur la base d'hypothèses concernant la grippe espagnole.https://t.co/mpnAXv…

RT @MartinFierro769: 54/n On a essayé d'établir une corrélation sur la base d'hypothèses concernant la grippe espagnole.https://t.co/mpnAXv…

54/n On a essayé d'établir une corrélation sur la base d'hypothèses concernant la grippe espagnole.https://t.co/mpnAXvjPme

@jeremyphoward This paper on Spanish flu might help Also, try looking for "infectious dose" (a more correct term) rather than viral load https://t.co/n6EShWuGqL

Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic #cdnpoli #uspoli #bcpoli #covid19 https://t.co/VU4smmQKLG

https://t.co/vkc6ZWHWtJ Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic A. Cristina Paulo ,Margarida Correia-Neves,Tiago Domingos,Alberto G. Murta,Jorge Pedrosa Published: July 26, 2010

https://t.co/Xh4W2pQ5P0

Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic Via:ncbi https://t.co/M3imnLBZy1

@DrTregoning @NYT @AdamJKucharski @Caroline_Bartma @igoodfel @bpaiig Thanks @DrTregoning. This carried me to https://t.co/l7xEg04SBe and https://t.co/t2Ux0fg71v which may give a better handle on our state of knowledge!

Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic https://t.co/DWNDYWycwH

@R_H_Ebright I’ve been screaming about the #infectiousDOSE @R_H_Ebright PLEASE read this super informative and illuminating scientific study done by @NIH based on the 1918 #GlobalPandemic https://t.co/wOnHJUbaLe #CoronavirusUSA #COVIDー19

RT @MoneywhoreTrump: This #scientific study from @NIH puts forward very strong #data #evidence from the 1918 #GlobalPandemic #SpanishFlu…

RT @MoneywhoreTrump: @MiamiHerald Hello 👋 @MiamiHerald - would you and your Twitter readers like to know why #super #healthy people with no…

RT @MoneywhoreTrump: @MiamiHerald Hello 👋 @MiamiHerald - would you and your Twitter readers like to know why #super #healthy people with no…

@MiamiHerald Hello 👋 @MiamiHerald - would you and your Twitter readers like to know why #super #healthy people with no underlying conditions get severely #ill 😷 ?? PLEASE PLEASE PLEASE #read this fascinating illuminating #scientific study from @NIH http

RT @MoneywhoreTrump: This #scientific study from @NIH puts forward very strong #data #evidence from the 1918 #GlobalPandemic #SpanishFlu…

This #scientific study from @NIH puts forward very strong #data #evidence from the 1918 #GlobalPandemic #SpanishFlu It has a very strong #hypothesis as to why #super #healthy people with no underlying conditions get severely #ill 😷 #CoronavirusUSA ht

@Jaden_Reports @3L3V3NTH Hello 👋 @Jaden_Reports and @3L3V3NTH ... would you both like to know why this happened to him ? PLEASE read this fascinating and illuminating scientific 🧪 study 📖 from @NIH https://t.co/wOnHJUbaLe #CoronavirusUSA #CoronaUpdate

PLEASE PLEASE PLEASE read this scientific study from @NIH @gregggonsalves @ScottGottliebMD @DrMattMcCarthy @MackayIM @EricTopol @DrEricDing @V2019N @sciencecohen @aetiology @HelenBranswell @BillHanage @ByMikeBaker @SiouxsieW @GermHunterMD @kakape @JeremyK

RT @InfectiousDz: Why are some outbreaks amplified? Why do some patients have such worse outcomes? Sometimes it may just be dose dependent…

RT @MoneywhoreTrump: #Coronavirus #CoronavirusUSA #Covid_19 #CoronaUpdate #CoronavirusOutbreak increase #CFR can be explained by the dyna…

RT @InfectiousDz: Why are some outbreaks amplified? Why do some patients have such worse outcomes? Sometimes it may just be dose dependent…

@yashar #Healthy people are dying of #CV with no underlying conditions- just like what happened during the #GlobalPandemic of 1918 @yashar would you like to know why? Well you can read this scientific study by @NIH https://t.co/wOnHJUbaLe

@MollyMcKew While we are on the subject of the 1918 #GlobalPandemic ... Just wait until you finish reading thru this #fascinating #scientific study from @NIH which answers the question WHY #healthy people with NO underlying conditions get severely #ill 😷

@aemajeste @xeni I’ve got an even BETTER article from @NIH for you all Based on the 1918 Global Pandemic One that answers many mysteries surrounding Global Pandemic #Covid_19 Such as why are healthy people with no underlying conditions getting severely

RT @jazzphillips3: Not an easy read, but asks the question, does the number of infected people you're around increase the viral load and in…

RT @jazzphillips3: Not an easy read, but asks the question, does the number of infected people you're around increase the viral load and in…

RT @InfectiousDz: Why are some outbreaks amplified? Why do some patients have such worse outcomes? Sometimes it may just be dose dependent…

RT @InfectiousDz: Why are some outbreaks amplified? Why do some patients have such worse outcomes? Sometimes it may just be dose dependent…

RT @jazzphillips3: Not an easy read, but asks the question, does the number of infected people you're around increase the viral load and in…

Not an easy read, but asks the question, does the number of infected people you're around increase the viral load and increase severity of infection and mortality?

RT @InfectiousDz: Why are some outbreaks amplified? Why do some patients have such worse outcomes? Sometimes it may just be dose dependent…

Please read this scientific study by @NIH @BillHanage

RT @InfectiousDz: Why are some outbreaks amplified? Why do some patients have such worse outcomes? Sometimes it may just be dose dependent…

RT @InfectiousDz: Why are some outbreaks amplified? Why do some patients have such worse outcomes? Sometimes it may just be dose dependent…

Why are some outbreaks amplified? Why do some patients have such worse outcomes? Sometimes it may just be dose dependent - large or multiple exposures. This has been the worry of many healthworkers https://t.co/XfIlTZZ2aY

Please read this scientific study from @NIH @CoronavirusCast @kr3at @CoronavirusSTEM @Chronolxgical @GlobaISpectator @NorbertElekes @DeItaOne @COVIDtracker @2019nCoVwatcher @felixdennis123 @cricketcrocker @WarsontheBrink @WilliamYang120 @alexandraphelan @

Please read this scientific study from @NIH @gorskon @YoniFreedhoff @meganranney @JohnsHopkinsSPH @JHSPH_CHS @yaneerbaryam @spatialepilab @HelenBranswell @ByMikeBaker @lookner @MichaelBurryBTC @R_H_Ebright @thehowie @akihheikkinen @KrutikaKuppalli @kakape

Please read this scientific study from @NIH @CoronavirusCast @COVID19Tracking @seattleflustudy @UWVirology @EricTopol @ScottGottliebMD @trvrb @MackayIM @florian_krammer @Laurie_Garrett @drmoupali @firefoxx66 @ETSshow @SandySpringerMD @darakass @GermHunter

RT @MoneywhoreTrump: #Coronavirus #CoronavirusUSA #Covid_19 #CoronaUpdate #CoronavirusOutbreak increase #CFR can be explained by the dyna…

Please read this scientific study from @NIH @DrRobDavidson @DrMattMcCarthy @DrAMcCullough @DrEricDing @VirusWhisperer @aetiology @DrTomFrieden @angie_rasmussen @drdanchoi @JenniferNuzzo @curefinder @SiouxsieW @KindrachukJason @JeremyKonyndyk @InfectiousDz

RT @MoneywhoreTrump: #Coronavirus #CoronavirusUSA #Covid_19 #CoronaUpdate #CoronavirusOutbreak increase #CFR can be explained by the dyna…

#Coronavirus #CoronavirusUSA #Covid_19 #CoronaUpdate #CoronavirusOutbreak increase #CFR can be explained by the dynamics of disease and by a dose-dependent response mediated by number of simultaneous contacts a susceptible person has with infectious ones

RT @MoneywhoreTrump: Influenza Infectious Dose We propose that the increase in the case-fatality rate can be explained by the dynamics of…

RT @MoneywhoreTrump: Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic…

Influenza Infectious Dose We propose that the increase in the case-fatality rate can be explained by the dynamics of disease and by a dose-dependent response mediated by the number of simultaneous contacts a susceptible person has with infectious ones. h

Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic https://t.co/wOnHJUbaLe

Lessons from 1918. Why social distancing is so important during a pandemic. #COVIDー19 #coronavirus Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic https://t.co/fRRspy2orP

Infectious Dose May Explain High Mortality of 1918–1919 Pandemic (2010) https://t.co/Hp4gAEgyA7

@Declanrooney88 @logimech1 @NoahHaber There's some evidence for this in animal experiments and possibly in natural settings e.g. https://t.co/zzS050FkAt I'd like to know if this also the case in Covid-19. I'm not the only one among my colleagues who consid

RT @_natachacouto_: @alanmcn1 Maybe this paper could help... https://t.co/Pl4ogyzOJp

@alanmcn1 Maybe this paper could help... https://t.co/Pl4ogyzOJp

@lrozen @jeremychrysler @ems1944 @murcoil @MarcellaGrid Did a quick search - this article may be of interest for this topic. Their conclusion: more contacts = higher dose —> increased fatality rate for later waves of 1918 flu https://t.co/pjTYSnfFQa

@_thebethpenalty Here is one paper on virus initial dose and severity. There are dozens. Also, early vaccines sort of worked this way a very tiny dose of the weakened virus results in a minor reaction and immunity. ie. Rabies https://t.co/2kxFB5Po3b

#COVID19 The amount of virus dose you get when infected is a factor in the severity of the case. So wearing a mask and washing is not just important to prevent getting infected but also to reduce the severity if you do. https://t.co/2kxFB5Po3b

@timeofmonsters_ https://t.co/2kxFB5Po3b A major factor in the Spanish Flu was viral dose vs. severity of the case.

RT @duremarik: @Rigsector @geomysl Да я вижу у них нестыковка. Вот статья получше, в ней говорится что CFR сильно менялся от волн эпидемии,…

@Rigsector @geomysl Да я вижу у них нестыковка. Вот статья получше, в ней говорится что CFR сильно менялся от волн эпидемии, но в целом возможно был 6 или чуть более: https://t.co/8c6pRqEU3F