Interesting, I didn’t know this about ATG5! Best case, yes, total AP and we can just activate it in adults (perhaps even suppress it in children!). Worst case, damn pleiotropy means it’s a trade-off… (Would be interesting to run the stats based on this!) h
RT @AlekseyVBelikov: @statto Their work suggests that ATG5 overexpression is the strongest rejuvenating factor. But it has been connected t…
@statto Their work suggests that ATG5 overexpression is the strongest rejuvenating factor. But it has been connected to the childhood asthma: https://t.co/7n1vQhCNgr. I guess this is antagonistic pleiotropy in action.
@ydeigin @gladyshev_lab Their work suggests that ATG5 overexpression is the strongest rejuvenating factor. But it has been connected to the childhood asthma: https://t.co/7n1vQhUo7Z. I guess this is antagonistic pleiotropy in action.
Functional Variant in the Autophagy-Related 5 Gene Promotor is Associated with Childhood Asthma. http://t.co/jlGdgQ5d