Will be giving this a read!
One of my highly cited papers was rejected by *7* of the top genetics journals without review before it was published in @PLOSONE. The reason? It provided an alternative perspective that editors didn't want out there. A great example of disciplinary bias.
Thanks to Scott Williams for mentioning our paper showing that SNP associations might not replicate in #GWAS due to allele frequency changes at a 2nd interacting SNP. Lack of replication doesn't mean a SNP assoc isn't real. https://t.co/2SiIxFFOA2 #epistas
RT @moorejh: Our paper on "Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture" is even more…
Our paper on "Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture" is even more relevant today as the interest in #epistasis analysis of #GWAS data grows. https://t.co/3XIKAfGzmu #genomics #bioinformatics
Highly recommend reading this! I have some results along the same line, focused more on heritability estimation, hopefully will put it online in the next couple of months.
:)
RT @PhilippBayer: well it kind of worked on google: https://t.co/ks65jD1SG2 and it was @moorejh ;)
well it kind of worked on google: https://t.co/ks65jD1SG2 and it was @moorejh ;)
RT @moorejh: Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture https://t.co/3XIKAfGzmu #gwa…
RT @moorejh: Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture https://t.co/3XIKAfGzmu #gwa…
What a timely paper (even though it's 10 years old) - I'm seeing some non-replicating GWAS results right now, good to cite!
RT @moorejh: Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture https://t.co/3XIKAfGzmu #gwa…
RT @moorejh: Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture https://t.co/3XIKAfGzmu #gwa…
Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture https://t.co/KvWtGm2dHs by @plosone #gwas
RT @moorejh: Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture https://t.co/3XIKAfGzmu #gwa…
RT @moorejh: Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture https://t.co/3XIKAfGzmu #gwa…
Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture https://t.co/3XIKAfGzmu #gwas #genomics #bioinformatics #epistasis
RT @GreeneScientist: #psb17 And Scott drops by to ask if he should have directly cited our paper on the topic. Here it is: https://t.co/vx…
RT @GreeneScientist: #psb17 And Scott drops by to ask if he should have directly cited our paper on the topic. Here it is: https://t.co/vx…
Nice paper @GreeneScientist - I hadn't seen it before. https://t.co/OQzqQdmL1H
#psb17 And Scott drops by to ask if he should have directly cited our paper on the topic. Here it is: https://t.co/vxc5Isx4xQ
RT @GreeneScientist: #CSIG16 Side note from Wen Wang's talk: gene-gene interactions & missed associations: https://t.co/vxc5IsftGi https:…
#CSIG16 Side note from Wen Wang's talk: gene-gene interactions & missed associations: https://t.co/vxc5IsftGi https://t.co/tmLtlPxqMM
Trudy Mackay paper (http://t.co/PdGNc4YsF4) shows epistasis + population-specific effects a la our 2009 paper http://t.co/S0MdLzXSVb in DGRP
@moorejh @McDawg You can get more accurate and comprehensive view of research engagement surrounding the paper here: http://t.co/043QkLqtDs
@delahar @WiringTheBrain #epistasis is unlikely to replicate as allele freqs & env shift. See http://t.co/Za6Y51k4Ru
@delahar @WiringTheBrain #epistasis is unlikely to replicate as allele freqs & env shift. See http://t.co/Za6Y51k4Ru
@PhilippBayer Maybe, but lack of replication is expected under some valid genetic models. http://t.co/Za6Y51k4Ru #GWAS #genomics
@PhilippBayer Maybe, but lack of replication is expected under some valid genetic models. http://t.co/Za6Y51k4Ru #GWAS #genomics
@ProfLHunter We wrote a controversial paper on the fallacy of replication under a complexity model. http://t.co/7FtYbDrC #GWAS #psb13
First, read our theoretical paper on "Failure to replicate #genetics associations" http://t.co/7FtYbDrC #genomics #GWAS
First, read our theoretical paper on "Failure to replicate #genetics associations" http://t.co/7FtYbDrC #genomics #GWAS
First, read our theoretical paper on "Failure to replicate #genetics associations" http://t.co/7FtYbDrC #genomics #GWAS
First, read our theoretical paper on "Failure to replicate #genetics associations" http://t.co/7FtYbDrC #genomics #GWAS
@genetics_blog @vubush Looking at non-replicated #GWAS hits is consistent with our simulation paper on the matter http://t.co/7FtYbDrC
@genetics_blog They should have read and discussed our paper on #epistasis replication :) http://t.co/7FtYbDrC
@dgmacarthur @michelebusby @girlscientist Failure to replicate a #GWAS hit tells you nothing about whether it is real http://t.co/5tIdVGgf
RT @GreeneScientist: "Most Reported Genetic Assoc. with IQ Are Probably False Positives" http://t.co/OfNYpDzq . http://t.co/4O3uGChp
"Most Reported Genetic Associations with IQ Are Probably False Positives" http://t.co/RKqCdIDV ignores epistasis http://t.co/KyiSLdbr
FWIW my article with a similar peer review experience to previous tweet ended up being cited heavily post-publication http://t.co/KyiSLdbr
RT @moorejh: @delahar Here is my paper on why interactions are not likely to replicate http://t.co/5tIdVGgf #GWAS
@delahar Here is my paper on why interactions are not likely to replicate http://t.co/5tIdVGgf #GWAS