| Title |
Clinical Relevance of Gain-Of-Function Mutations of p53 in High-Grade Serous Ovarian Carcinoma
|
|---|---|
| Published in |
PLOS ONE, August 2013
|
| DOI | 10.1371/journal.pone.0072609 |
| Pubmed ID | |
| Authors |
Hyo Jeong Kang, Sung-Min Chun, Kyu-Rae Kim, Insuk Sohn, Chang Ohk Sung |
| Abstract |
Inactivation of TP53, which occurs predominantly by missense mutations in exons 4-9, is a major genetic alteration in a subset of human cancer. In spite of growing evidence that gain-of-function (GOF) mutations of p53 also have oncogenic activity, little is known about the clinical relevance of these mutations. |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 1% |
| India | 1 | 1% |
| United Kingdom | 1 | 1% |
| Canada | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 88 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 18% |
| Student > Bachelor | 13 | 14% |
| Researcher | 11 | 12% |
| Student > Master | 11 | 12% |
| Other | 8 | 9% |
| Other | 13 | 14% |
| Unknown | 20 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 23 | 25% |
| Agricultural and Biological Sciences | 20 | 22% |
| Medicine and Dentistry | 16 | 17% |
| Environmental Science | 2 | 2% |
| Mathematics | 2 | 2% |
| Other | 6 | 6% |
| Unknown | 24 | 26% |