@sabbatiello0310 @slavov_n Been there, most notably for the "ortholog conjecture" paper https://t.co/U5oqgaLTZA. Oh, did we upset the world. Criticism was both harsh and personal. But the paper stands! Response? We had a response paper a decade later (ISMB
.@3rdreviewer just gave a nice review of the results (and reactions to) his 2011 ortholog conjecture paper. Now moving into he and his colleagues' most recent analysis: https://t.co/siTxYaWNoZ #ISMB2020 https://t.co/NXoH4lcMQm
RT @marc_rr: @cdessimoz starts with Nehrt et al @3rdreviewer vs @AdrianAltenhoff et al #ISMBECCB https://t.co/8TqqMhJ1ty https://t.co/hT8lo…
@cdessimoz starts with Nehrt et al @3rdreviewer vs @AdrianAltenhoff et al #ISMBECCB https://t.co/8TqqMhJ1ty https://t.co/hT8loQApSb
RT @marc_rr: @RomainStuder Then in 2011 Nehrt et al (@3rdreviewer) published a paper claiming more evolution of gene function between ortho…
@RomainStuder Then in 2011 Nehrt et al (@3rdreviewer) published a paper claiming more evolution of gene function between orthologs than between paralogs. https://t.co/8TqqMhJ1ty
Rereading this by @3rdreviewer &al. Gearing up for in-class debate. Make the Ortholog Conjecture Great Again https://t.co/GJ7w0QYiYi
RT @marc_rr: Matt's paper on orthologs: http://t.co/kkcJY8Sx #smbe12
Matt's paper on orthologs: http://t.co/kkcJY8Sx #smbe12
orthologs more functionally similar than paralogs (http://t.co/dYcfHc4o) ; other work claimed the opposite (http://t.co/0gv55bwt)
#PLoS: Testing the Ortholog Conjecture with Comparative Functional Genomic Data from Mammals http://t.co/WSArPS4
RT @iddux: Wyatt shows that paralogs actually give better annotation transfer than orthologs. http://bit.ly/nWShuB #AFPCAFA11 #ISMB
Wyatt's claim runs contrary to common wisdom. Which is good :) http://bit.ly/nWShuB #AFPCAFA11 #ISMB
Wyatt shows that paralogs actually give better annotation transfer than orthologs. http://bit.ly/nWShuB #AFPCAFA11 #ISMB
Paralogs better indicator of function than orthologs, even with lower amino acid identity #bioinformatics http://t.co/ATBcZRs